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The loss or decrease of expression of the transferred gene after several weeks, especially in adenoviral vectors, is one of the major and most frequent challenges in gene therapy.
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Imaging of the degenerative spine is a frequent challenge in radiology.
The accurate changepoint detection of different signal segments is a frequent challenge in a wide range of applications.
A frequent challenge in these kinds of experiments and validations is the lack of a stable, reproducible and flexible biological reference material.
Addressing delusions presented by patients in the first meeting is a frequent challenge in acute care.
They each address problems of complexity, which is a frequent challenge in global health.
The main argument was that extra-articular manifestations are rather frequent in AS and the entire spectrum of spondyloarthritis, 39 and that they constitute a frequent challenge in management that clearly requires cooperation between specialities.
Analysis and visualization of large collections of molecules is one of the most frequent challenges cheminformatics experts in pharmaceutical industry are facing.
The current obesity epidemic presents frequent challenges to the obstetrician.
We hypothesize that this characteristic expression pattern of gTLR2-1 is associated with the habitat of the goose, and that frequent contact with microorganisms in the water may increase the expression of TLRs due to frequent challenge by pathogenic bacteria.
Though most participants experienced ethical issues related to "staff management", the fact that "patient care" came second to this shows that nurses at managerial positions still continue to face frequent ethical issues challenges in "patient care".
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com