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Unfortunately, bonding orthodontic attachments on nanofill composite resin may result in more frequent bond failure than bonding to other composite resins, as reported by previous studies [13, 18].
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So, s2m tool supplies a set of rules describing the most frequent bonds observed in biological polymers.
For same number of attachment points, the more frequent bonds linking the residue to others, the better because polymers are mainly synthesized by one (or few) major type(s) of bonds and less frequent other types.
The snapshots shown in Figure 7 were extracted from the trajectories according to the most frequent hydrogen bond pairs (See Methods).
Similarly to the protein-organic compound complexes, the most frequent hydrogen bond incorporates the NH- group of a residue that serves as the donor and the oxygen atom of a ligand.
The binding modes depicted in Figure 6 were determined by selecting the simultaneous and most frequent hydrogen bonds between the peptide backbone and NQTrp (see Table S4).
The most frequent hydrogen bonds involving the peptide backbone are NH1-CO, CO1-NH and CO3-NH (Figure S4, Table S4).
In addition, the most frequent hydrogen bonds with the peptide backbone of Aβ involve the quinonic carbonyls moieties, the anilinic nitrogen and the carboxyl group of NQTrp (Figure S4, Tables S4 and S5).
The five hydrates exhibit the two most stable and most frequent hydrogen bonding motifs on the crystal energy landscape Figure 2a.
This practice is all too frequent in the bond market.
However, polymerization stresses originating from the volumetric shrinkage of resin composites and hydrolysis of the hybrid layer/adhesive material are considered the most frequent reasons for bonding failure [1],[1]]-[1]].
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