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Furthermore, conservation signal is highest in frequent binding partners while progressively lowered from occasional to rare binding partners.
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A target (66) and frequent binding partner of vasoinhibins is plasminogen activator inhibitor-1 (PAI-1).
FOXA1, an essential determinant of ERα expression [ 30] and a frequent binding partner of ERα and GATA3 [ 17, 31], decreased in abundance following estradiol treatment in T47D, although not to the same extent as GATA3 and ERα.
Most huntingtin partner proteins ("binding partners") bind to one of its end segments.
Most proteins bind their binding partners in the native confirmation.
Another typical case is that binding partners are phosphorylated on binding sites and bind other effectors.
FANCM binding partners FAAP24 and MHF stimulate FANCM-DNA binding activity17,18,25.
This was then used to search for binding partners on the surface of the egg.
Polyvalent interactions enhance functional affinities between binding partners by favoring ligand rebinding after an initial binding event occurred37,38,39.
Oxidized derivatives of cholesterol with biological activity, for example, as binding partners for nuclear receptors.
Lee, H. J. & Zheng, J. J. PDZ domains and their binding partners: structure, specificity, and modification.
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