Sentence examples for frequency variants from inspiring English sources

Exome genotyping arrays to identify rare and low frequency variants associated with epithelial ovarian cancer risk.

Rare and low frequency variants are not well covered in most germline genotyping arrays and are understudied in relation to epithelial ovarian cancer (EOC) risk.

Viral population structure was organized into a limited number of clusters that included the dominant variants combined with multiple clusters of low frequency variants.

Next generation viral quasispecies evolved from low frequency variants at earlier time points through multiple non-synonymous changes in lineages within the evolutionary landscape.

For lower frequency variants (MAF ≤5%), power to detect an association remained low.

Furthermore, analysis of low frequency variants in additional large families and different ethnic groups may increase the pool of variants.

"But it's been difficult to pinpoint the genetic cause, probably because it's linked to low-frequency variants," says Marini.

Wang, J. et al. Investigation of rare and low-frequency variants using high-throughput sequencing with pooled DNA samples.

Zeng, K., Fu, Y.X., Shi, S. & Wu, C.I. Statistical tests for detecting positive selection by utilizing high-frequency variants.

This variant, together with two low-frequency variants in exon 3 (rs202023509 and rs202237352), was confirmed by Sanger sequencing, as shown in Figure 2e, f).

Patrick Sulem, Daniel Gudbjartsson, Bragi Walters and colleagues identify two low-frequency variants associated with serum uric acid levels and gout in the Icelandic population.