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Due to their unison singing, the singing frequency, repertoire sizes and repertoire composition, i.e. all features of the learned song were similar between males and females as described previously [16], [17] (Fig. 1).
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The frequency and repertoire of stereotypies were significantly higher in the indoor bears irrespective of enclosure size.
We investigated the contribution of memory B cells and long-lived plasma cells to SPS, by analyzing changes in antibody titers and specificities, frequency and repertoire of specific memory cell before and after rituximab treatment in a pair of monozygotic twins suffering from SPS [21].
Pearson correlation coefficient analysis was performed to determine whether the expression frequency of TCR repertoire correlated with its restriction frequency in allochimeric molecules-induced tolerant recipients.
The size of each clone was calculated based on its frequency in the repertoire.
Since Evenness profiles are SR-scaled versions of diversity profiles, it follows that they also represent immune repertoire frequency distributions to a high degree (Fig. 3).
Having shown that immune repertoire frequency distributions are faithfully captured by diversity profiles (Figs. 2 and 3), we applied hierarchical clustering, SVMs and feature selection to diversity profiles and showed that they accurately predict immunological status (Figs. 4 and 5, Table 1).
Haplotype frequencies for KIR repertoire were estimated with maximum likelihood function [ 25].
As seen for the heavy chain repertoire, the frequency of several Vλ germline genes changed during the selection process.
Identifying single nt mismatch sequences compared with a higher frequency index sequence in repertoire analyses can be performed through straightforward algorithms, and a threshold frequency value can be assigned to flag such sequences as potential mis-sequence events.
As opposed to single diversity values, our profile-based framework enabled the reliable capture of immune repertoire clonal frequency distributions, and thus, the majority of potential immunological information coded therein.
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CEO of Professional Science Editing for Scientists @ prosciediting.com