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And when she applied estimates of the speed of mutation to her results, the ages coincided neatly with the Neolithic agricultural revolution.Dr Tishkoff and her colleagues studied the frequency of variants in the human G6PD (glucose-6-phosphate-dehydrogenase) gene, which confers resistance to malaria.
The frequency of variants across chromosomes that is related to their size is different between parents at each chromosome but rare between the monozygotic twins (Fig. 3).
To investigate the frequency of variants in 3 major age-related macular degeneration (AMD -associated loci in pAMD -associatedpean-American descent with polociinal choroidal vasculopatientsCV).
Comparison of the frequency of variants differed from EP in both groups of patients (P=0.01) with an odds ratio (OR) of 5.14 (CI 95% [1.07 26.56]).
By comparing the variants of these genes in the ancient skeletons with those in 60 modern-day Ukrainians, as well as a larger sample of 246 modern genomes from the surrounding region, the team found that the frequency of variants related to lighter skin and hair, as well as blue eyes, increased significantly between the ancient and modern populations.
Comparison of the measured frequency of variants by pyrosequencing, or the calculated frequency of variants by Sanger sequencing, showed that both methods produced comparable results across a range of frequencies (Table 1).
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In Figure 11 is presented the distribution of the average frequency of variant nucleotidic sites (when compared with the outgroup sequences) in the two Atlantic species.
Female gender, older age, and pregnancy are risk factors for chronic venous diseases [24] and women have greater frequency of variant hepatic veins [25].
The total frequency of variant TPMT alleles was 8%.
The frequency of variant 6 in each group was evaluated by Fisher's exact probability test.
Let x i be the frequency of variant 1 in group i.
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