Sentence examples for frequency of substitution from inspiring English sources
Our analysis demonstrated that the vast majority of differences in the frequency of substitution between LTRs and flanking NRRs could be ascribed to mutations possibly affecting cytosines (G C ->A T) which are targets of DNA methylation.
However, in the simulated finisher diet, DDGS had a higher substitution rate in terms of quantity, but at a lower frequency of substitution over the study period compared to the starter and grower diets.
In this analysis, the frequency of substitution direction in rat may be effected by some nucleotide substitutions occurred in the common ancestor of mouse and T. muenninki.
The significance of cross-species differences within the region of overrepresentation was then assessed according to the background frequency of substitution (supplementary material S2, Supplementary Material online).
To quantify the significance of cross-species differences, we considered a "background" frequency of substitution toward each pair of nonidentical nucleotides.
We have characterized these nucleotide substitutions by comparing them with high-quality SNPs from dbSNP, both in terms of sequence context and frequency of substitution types.
In another scenario (Fig. 8b), simpler at least in terms of the frequency of substitutions, the aspartic acid was substituted only once to a glutamic acid before the divergence of all the land plant PRR subfamilies.
In contrast, when the frequency of substitutions is compared between bases that are normally not methylated, no significant differences could be identified between LTRs and flanking NRR tracts.
Only the amino acid positions significant for frequency of substitutions (in the amino acid substitution test above) were evaluated here.
For example, the frequency of substitutions from valine to isoleucine in the nonpolar, aliphatic R group was 2.4% in group [S-C], but 0.6% in group [M-C].
Similarly, the frequency of substitutions from isoleucine to valine in the nonpolar, aliphatic R group was 1.8% in group [S-C], while it was 0.4% in group [M-C].
