Sentence examples for frequency of responding from inspiring English sources

Equally important, the frequency of responding CD4+ cells for a particular target protein is typically low.

The frequency of responding cells, obtained after subtracting background spots in negative control wells (medium alone), was expressed as spot-forming cells per million PBMC.

These assays, however, are still based upon functional assays and the frequency of responding T cells may not necessarily be the same as the frequency of T cells expressing the appropriate T cell receptor [6].

However the frequency of responding patients was low (20%, Fig. 6A) and healthy donors showed reactivity against this epitope only upon depletion of CD25+ T cells, albeit only in two out of four individuals.

In the cytomegalovirus-specific CD4+ memory human T-cell model, an increasing co-stimulation increased the frequency of responding CD4+ T cells, and IFN-γ producing cells also produce IL-2 with increased co-stimulation.

That the frequency of responding CD4+CD28null T cells was higher in the synovial fluid compared with the peripheral blood does not necessarily mirror an accumulation of HCMV-reactive CD4+CD28null T cells in this compartment, since the same effect was seen for CD4+CD28+ T cells (data not shown).

We conclude that the vaccine was both safe and remarkably immunogenic, leading to frequencies of responding T cells that appear to be much higher than those induced by any other influenza vaccination approach.

In AAV-HBV injected mice, cytokine-producing cells were detected in both experiments, albeit with distinct frequencies (percentage of responding mice ranged from 20% to 60%).

A study from Nicaragua reported a frequency of 11% of responding farmers having experienced symptoms of intoxication after spraying during the last month, 25% in the last 12 months and 48% at one point in time [ 8].

We established that in this pentamer assay, in vitro stimulation with TB10.3/4:20 28 peptide did not modify the frequency of the responding mice, compared to ex vivo analysis.

Therefore, following in vitro stimulation, the sensitivity of this assay is improved without biasing the frequency of the responding mice or the relative importance of CD8+ T-cell responses in different mice.