Sentence examples for frequency of replication from inspiring English sources
Any perturbation of the frequency of replication origin firing will induce replicative stress which in turn activates p53 and downstream events, including apoptosis [46].
To analyze the frequency of replication in the putative stem cell niche, we used the BrdU retaining technique.
As expected, the frequency of replication in malignantly transformed cells was markedly increased (Fig. 2).
Because of the low frequency of replication and apoptosis, and the relatively small number of women in the post-partum group, the data were insufficient to be meaningful.
This inhibitor-target mechanism is based on the negative control of the frequency of replication initiation events, mediated by the interaction of two RNA molecules, RNAI and RNAII and Rop (repressor of primer), a protein consisting of 63 amino acids.
Ki67 (a marker of proliferation) labeling of the pancreata showed that all individuals had a low frequency of replication, although there was a trend toward decreased beta cell replication with age.
However, the method for calculating the frequency of replication-competent virus in this previous report is not necessarily sensitive enough.
Siliciano et al. calculated the number of latently infected cells as the frequency of replication-competent virus per 1 million CD4+ lymphocytes in peripheral blood and reported that their half-life was about 44 months [ 2].
To examine the effects of allele frequency on replication of main effects when there is an underlying complex disease æ tiology we first generated genetic models.
Generation-time-like effects have also been tested for in organism such as RNA viruses where faster substitution rates were correlated with higher frequencies of replication [ 16] and in spore-forming bacteria where rates of divergence were not related to spore dormancy [ 17].
More thorough simulations to assess the impact of sample size, allele frequency, number of replication groups, and noise filter applications are needed in the future to understand these issues in detail.
