Sentence examples for frequency of gains from inspiring English sources
Cluster B3 was characterized by the highest frequency of gains on 7p (93%), and the highest frequency of EGFR mutations (93%), although these abnormalities did not coincide.
Minimal common regions (MCR) of gain and loss were defined as the smallest group of contiguous SNPs (≥3) with a high frequency of gains and losses (Z-score threshold ≥2.1) according to the overall distribution of CN values found in the entire tumour cell genome, respectively.
On a genome-wide profile, SCCs showed higher frequency of gains than ACs (p = 0.067).
Some dissimilarities were apparent, in particular the lower frequency of gains reported elsewhere at chromosomes 1, 19 and 20.
We examined the frequency of gains and losses in the subgroups identified by immunostaining of GCB DLBCL.
We examined the frequency of gains and losses in the BCL6+ non-GCB and BCL6− non-GCB groups.
Given the frequency of gain and amplification of 1q (21.9% and 6.1%, respectively in this study) and the impact on the outcome, either addition of these features, or revision to classify them as part of the high-risk definition in the R-ISS and IMWG risk stratification methods could improve the current risk criteria [13, 14].
Firstly, we selected those known genes with a high frequency of gain (>40%), that were differentially expressed (n = 629).
PIK3CA, encoding the PI3K catalytic subunit, is the oncogene exhibiting a high frequency of gain-of-function mutations leading to PI3K/AKT pathway activation in breast cancer.
For example, 20q has long been recognised as having a high frequency of gain, yet the proposed target gene(s) vary from study to study.
