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The primary outcome measure was the frequency of deviation from the initial treatment plan from baseline to 54 weeks between the two groups.
Although the frequency of deviation from the expected profile is significantly higher than that due to outcrossing, it would have been better to grow the plants in isolation.
Comparison of frequency of deviation across patient groups (that is, criteria-based versus DAS28-based cohorts) and baseline disease activity (HDA versus (LDA + MDA)) was assessed using the chi-square test.
Of the defined stem-loop structures, loop 1 showed the highest frequency of deviation from the canonical 'ATCG' sequence, with approximately 10% (20/202) of repeat A units harboring an 'AACG' tetraloop instead (Additional file 2: Figure S2).
In this instance, the control range of CQAs is the risk acceptance criteria and the extent and frequency of deviation from the CQA control range may be considered in risk evaluation.
Balance indices were defined using the maximum deviation, which describes the maximum displacement of the projected COM relative to the BOS, as well as the deviation frequency, which describes the frequency of deviation of the projected COM from the BOS in these deviations.
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These histograms more readily visualise the frequency of deviations, the groups of deviations and the breadth of the spectrum of deviations.
The over all frequency of deviations is also under-represented in this analysis as only internal flags in the FDM sequence were considered.
An alternative method of checking the error rate is to measure the frequency of deviations from Mendelian inheritance.
A specificity of 0.99 and a frequency of deviations from the reference sequence in the order of 1 per 1000 sites would be expected to lead, on average, to ∼10 false-positive findings to one true variant position.
Driver feedback offers information (such as location, fuel consumption and the frequency of lane deviation) whereas driver support makes it possible to improve performance based on the information available through feedback (e.g. a better route, how to reduce fuel consumption, how to make fewer lane deviations).
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com