Sentence examples for frequency of a mutation from inspiring English sources

"It is the fastest change in the frequency of a mutation described in humans," said Professor Nielsen.

Figure 5A demonstrates the extent to which the frequency of a mutation can be skewed by negative selection during the course of an infection.

If one assumes that the frequency of a mutation is related to the selection coefficient by, can be roughly estimated by comparing the frequency observed at different generations.

Furthermore, it is known that there is an inverse relationship between evolutionary constraint and the allele frequency of a mutation segregating in human populations, implying a direct relationship between interspecies divergence and fitness in humans.

If the noise level exceeds the expected frequency of a mutation, the variance of the associated waiting time estimator becomes large, because the true frequency cannot be accurately recovered.

Conversely, higher thresholds of conservative classifiers, such as –0.5, reduce the frequency of a mutation being classified as pathogenic, consequently predicting a smaller set of more reliable disease-associated mutations.

To clarify, this result provides a quantitative prediction of the ratio of the frequency of a neutral mutation after a generation to the rate of such mutations.

The relative frequency of a particular mutation within a gene is typically used as a criterion for identifying a driver mutation.

The overall carrier frequency of a CARD15 mutation in CD was 50.5%.

This seems to be the major cause of the decreased frequency of a BRAFV599R mutation in anaplastic carcinomas.

The frequency of a BRAFV599R mutation in anaplastic carcinomas is about half of that in papillary carcinomas.