Globally the frequency of disorder is rising gradually; patients suffering from this disorder are unable to turn out or respond properly to insulin produced in the body [ 2].
The various consequences of climate change include extreme climatic events such as super typhoons, extreme snowfall, and heat waves, and in fact, the frequency of such events is rising rapidly globally.
John Paul reminded me that the frequency of the planet is rising, that cultures are changing, and the main thing is to be involved, that "your way is the right way" as long as it doesn't hurt anyone else.
Epidemiological data demonstrate that the frequency of Candida infections is rising [ 3- 6], along with an increase in the proportion of infections caused by non- albicans Candida species that are intrinsically resistant or variably susceptible to fluconazole [ 7- 10].
The frequency of individually unique cancers is rising in light of emerging trends toward personalized medicine that relies on genetic testing and seeking specific biomarkers that reveal the presence of unusual cancers.
The frequency of type 1 diabetes is rising in almost every national population (4– 6).
The frequency of OPPP-infected individuals is rising and will likely continue to rise as the number of at-risk individuals is increasing.
The frequency of metastatic brain tumours is rising; this increased incidence is due, in part, to an ageing population, improved neuroimaging and increased patient survival following primary tumour treatment [ 7].
A prime example of such a tumor subtype is invasive lobular carcinoma (ILC) of the breast - the second commonest histology after invasive ductal carcinoma (IDC) - which accounts for 5-155-15%primary breast tumors and, unlike IDC, is rising in frequency [ 2].
