When both data on season and the sporozoite status were combined, the difference in kdr allelic frequency was even more pronounced.
This unusual frequency was even more notable for the strongest winds (which are more consistent with the mistral), representing 93.5% of the wind in November to December 1998 but only 63.1%, 47.7%, and 85% in November to December 1996, 1997, and 1999, respectively.
A high frequency becomes even more important in case providers experience uncertainty regarding the net gains of improvement efforts (as in relative schemes) because, compared to schemes involving little uncertainty, possible gains will be discounted at higher rates.
Considering that the size of the CD4+ T cell population in gp250 SC mice was around 40% of the CD4+ T cell population in B6.K mice, the augmented MCC-tetramer+ frequency was even more impressive.
For instance, most molecular models of evolution assume that state frequencies, and even more importantly, substitution rate frequencies do not change over evolutionary time, assumptions incorporated in likelihood/Bayesian methods which tend to model molecular evolution as stationary, homogeneous Markov processes [ 100].
The improvement of DR-based PFC over conventional generators in the frequency profile is even more significant as shown in Fig. 8.
The opposite effects of the low and high frequency sounds were even more pronounced during the sustained late phase of the response (Fig. 4E, right side).
Furthermore, it should be recalled that in the saccadic task, the images were centred at 5° of eccentricity, where low spatial frequency processing is even more important than in the rating task, which used free viewing.
The difference in InsG frequency may be even more pronounced since the exclusion of InsG at identical positions in the cII-gene as well as in the G-run probably leads to an underestimation of the actual frequency of InsG in spermatozoa.
Such a marked variation in the allele frequency spectrum is even more impressive in light of the strong linkage disequilibrium between the two exons in Europeans (see Additional File 2).
