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Two word frequency databases were used.
We thank Ms Wen-Ting Fan for constructing CPA and allele frequency databases.
To quantify the risk of SNP disclosure to relatives, we demonstrate a model for inferring sibling genotypes using proband SNP data and population-specific allele frequency databases, such as the HapMap[ 10, 11].
However, the rapid accumulation of data from familial testing and the availability of updated population frequency databases have resulted in improved variant classification and overall decreases in inconclusive result rates.
In addition, we establish individual-level allele frequency databases that provide SNP annotation, allele frequencies and the summary statistics for the HapMap samples for both the Affymetrix Human Mapping 100K and 500K Sets.
Therefore, we undertook an in-depth investigation of the relationship between CPA and important factors including sample size, time of data acquisition, effects of laboratory site, type of gene chip, ethnicity effects, and phenotypic status, and we constructed new public CPA and allele frequency databases.
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An F2 region critical frequency database, from 75 ionosonde stations and 25 storms, covering a full solar cycle, was built as the basis of the STORM Time Empirical Ionospheric Correction Model.
Reducing the size of the training images resulted in a decreased mapping quality, as the frequency database only represents local characteristics of landforms that are not representative for the remaining area.
HLA allele frequencies of Africa, Indian Ocean, Asia, Europe and USA were extracted from the Allele Frequency Database [43] and used for the current analysis.
Furthermore, KIR genotype profiles were assigned to the AA and Bx haplotype groups using the New Allele Frequency Database: http://www.allelefrequencies.net [20].
The second word frequency database we employed is the Sydney Morning Herald Word Database, which contains frequency and density figures from one full year (1994) of newspaper publication, amounting to more than 23 million words in 38,526 articles.
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