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Genotype frequencies were evaluated using the Hardy-Weinberg equilibrium test.
Differences between cases and controls with respect to allele frequencies were evaluated using the Chi-Square test using SAS 8.2.
Differences in detection frequencies were evaluated using the Fisher's exact test, and differences in median concentrations were evaluated with the nonparametric Wilcoxon rank sum test for chemicals with at least 50% detects >MRL.
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The difference between observed vs. expected frequencies was evaluated using a one-way χ2 Goodness-of-fit test.
Differences in allele frequency were evaluated using Fisher's Exact test.
Significant differences in CNA frequency were evaluated using the Fisher's exact test.
Group differences in mean daily stool frequency were evaluated using ANOVA and adjusted for multiple testing using the Bonferroni method.
Headache frequency was evaluated using the Headache Index (HI), i.e. the number of headache days per month.
Symptom frequency was evaluated using a 4-point Likert scale (i.e., 1 = rarely, 2 = occasionally, 3 = frequently, 4 = almost constantly).
Differences between PvL variables were assessed by means of Student's t test with the non-parametric U-Mann–Whitney test, while those between allelic frequencies variables were evaluated using the Pearson χ2 test with Yate's correction or Fisher's exact test, when appropriate.
Differences in genotype frequencies between groups were evaluated using Fisher's exact test, when appropriate.
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