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We first observe that the optimized solution prescribes a more accurate quantization at higher frequencies, since these convey more information on the time delay, as per the CRB (13), while all frequencies contribute in equal manner to the estimate of the phase offset as per (14).
While θS is only influenced by the number of segregating sites in the dataset, π is sensitive to allele frequencies at segregating sites, such that alleles at intermediate frequencies contribute more than alleles at low frequencies.
From the ACMG-recommended list of 24 conditions, those with the highest variant frequencies contribute between 99 and 99.9% (the top 11 and 19 conditions, respectively) to potential IFs.
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The first is that schizophrenia is highly polygenic, with hundreds and possibly thousands of distinct loci involved at the population level, and alleles with a spectrum of population frequencies contributing to risk.
He guided the lower frequencies, contributed backing vocals and is credited as co-producer on three tracks.
Both methods have suggested spatial frequency selective processing with only certain frequencies contributing to the brightness.
Drowning also revealed marked annual cycles (17.8%), and no other frequencies contributed significantly.
The genetic architecture of osteoarthritis is likely to be polygenic with multiple variants along the spectrum of allele frequencies contributing modest and small effects.
To visualize this, we went through the most significant peaks (from table 1) and looked at individual founder haplotype frequencies contributing to change between the young and old pools (supplementary fig. S6 a h, Supplementary Material online).
SC-BLSOM and the conventional BLSOM give similar patterns, showing that the SC-BLSOM can also unveil species-specific (and phylotype-specific) characteristics of oligonucleotide composition, by visualizing a major combination of oligonucleotide frequencies contributing to sequence clustering (self-organization).
It should be noted, however, ka- and kb-components above the critical frequency contribute almost equally to both normal and shear stresses, regardless of the duration of the force.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com