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Work at the CIRAD was supported by the French Genomic ANR 2008 CITRUSSEQ project.
This work was founded by the French Genomic ANR 2008 CITRUSSEQ project.
The French genomic evaluation model is an extension of the marker-assisted evaluation approach of Fernando and Grossman [ 8], using haplotypes of three to five single nucleotide polymorphisms (SNP).
The Dutch/Flemish genomic predictions used a Bayesian mixture model for SNP effects, along with polygenic effects [ 16], assuming that most SNP had small effects and a few SNP had moderate or large effects and the French genomic predictions used a mixed linear model with a polygenic effect and random haplotype effects across the genome [ 17].
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Parentage was tested following the French routine genomic selection procedure, using both 50K and HD datasets (S. Fritz, personal communication).
The Passiflora edulis BAC library consists of 82,944 individual BAC stored clones in 216 (384-wells) plates and is kept at the French Plant Genomic Resource Center (CNRGV).
Coding regions of GALT1, GALT3, and GALT4 were obtained from the RIKEN Bioresource Center, while the coding region of GALT6 was obtained from The French Plant Genomic Resource Center (http://cnrgv.toulouse.inra.fr/).inra.fr/
The most convenient model for genomic evaluation in French dairy goats would be the multi-breed model using a single-step approach.
With the recent availability of the Illumina goat SNP50 BeadChip [ 1], it has become possible to study the implementation of genomic selection in French dairy goat.
Using a commercial 385 K array-based comparative genomic hybridization (aCGH) genome array, we performed CNV discovery using 10 chicken samples from four local Chinese breeds and the French breed Houdan chicken.
French et al. [34] studied the genomic determinants of methotrexate polyglutamates (MTXPGs) variation in acute lymphoblastic leukemia (ALL), and found that ME2 is among 7 genes which displayed all 3 types of genomic variation associated with MTXPGs.
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