Sentence examples for free to activate from inspiring English sources

These subunits are then free to activate their 'target' proteins: Gβγ activates GIRK.

Both parts are then free to activate their downstream targets [ 22].

However, if the survival kinase signal is insufficient, Hdm2 remains unphosphorylated, stays in the cytosol 32, 33, leaving p53 free to activate its target genes, including Bax 34.

Bid and Bim engage a greater number of pro-survival proteins neutralizing their antagonism of Bak and Bax, and increase the likelihood that sufficient Bak or Bax are free to activate apoptosis.

In planarians that had experienced amputation, the inhibition of follistatin which leaves activin free to activate the TGF-β signalling pathway blocked key cellular and tissue remodelling events associated with tissue loss, and prevented regeneration.

Once MCC is extinguished, Cdc20 becomes free to activate the APC/C which targets Securin and Cyclin B for degradation, thus leading to sister-chromatid separation and mitotic exit.

Following correct attachment of all chromosomes to the spindle, the checkpoint is inactivated and Cdc20 is freed to activate the APC/C (Yu, 2002).

Because the reaction does not proceed, we can conclude that either (1) Zn2+ and Mn2+ are in complex with BSH and there is no free metal to activate the enzyme or (2) Zn2+ is competing with Mn2+ in the active site of FosB Sa and inhibiting the enzyme.

Aux/IAA degradation leads to dissociation of the co-repressor and HDA19; this is thought to free MP to activate gene expression (Chapman and Estelle, 2009).

However, during blastema formation and regeneration, Rb1 hyperphosphorylation is associated with sufficient free E2f1 to activate ARF, which inhibits fin regeneration via a Tp53-dependent mechanism.

It took about two months for a voting credential to arrive in the mail, and then she had to call a toll-free number to activate it.