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They also showed reductions in their levels of free, circulating androgens, the male hormones known to cause acne, suggesting that hormones played a role.
("Seventeen copies sold, of which 11 at trade price to free circulating libraries beyond the seas. Getting known," says Krapp in the play bearing his name some two decades later, finely balancing sarcasm and delusion).
Impact of free circulating mtDNA on endothelial cell is not known.
The ELISA for InO provided adequate sensitivity (200 ng/mL mAb equivalent) with relatively poor drug tolerance; interference from free circulating drug was observed at 100 ng/mL.
Peripheral blood samples containing circulating tumor cells (CTC) and free circulating tumor DNA (ctDNA) may provide a source to measure biomarkers prior to treatment.
Free circulating mitochondrial DNA (mtDNA) is elevated in a wild range of critical illness observed in intensive care units, and is associated with bad outcomes and mortality.
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Cell-free circulating DNA containing tumour-specific sequences can be identified in the plasma of cancer patients.
Cell-free circulating DNA (nucleosome) was also measured on plasma samples by Cell Death Detection ELISAPLUS kit (Roche, Boulogne-Billancourt, France) according to the manufacturer's instructions.
In particular the analysis of cell-free, circulating nucleic acids such as microRNAs (miRs) can reveal altered expression patterns indicative of mechanism of drug action, cancer growth, and tumor stroma interactions.
This study is the first to investigate the use of plasma levels of cell-free circulating nucleic acids (CNAs) as a marker of P. vivax malaria morbidity.
Another potential cancer biomarker is the cell-free circulating DNA in serum/plasma.
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