Sentence examples for free assays from inspiring English sources

Despite these biophysical similarities with Wt-Ub and the facile incorporation of K6W-Ub into conjugates in cell free assays, these conjugates are not degraded effectively in vitro and in vivo [19].

Physical interaction with the drug, demonstrated by cell free assays, is sufficient to alter nucleic acid properties and recruit the DNA damage repair system.

Most kinetic data available in the literature on α/β-secretase activity were obtained in cell free assays with purified enzyme and artificial peptide substrate.

The alpha helical content of purified PrP is decreased by binding to PPS, which has been proposed to increase the susceptibility of the protein to conversion in cell free assays by reducing the transition barrier [38].

Cell free assays of HDL oxidation.

Cell free assays showed that APTX removes AMP from 5′-termini at DNA strand breaks [8,10,25].

The development of "label-free" assays addresses many of these limitations, but current approaches still lack the throughput needed for applications in drug discovery.

One MilliporeSigma system user is developing label-free assays to distinguish blood cancers.

This could be demonstrated also in cell-free assays, where in addition presenilin-1, the catalytic subunit of the γ-secretase complex, was shifted out of lipid rafts.

The dissociation of the polymeric shell under reducing conditions and the subsequent release of protein were confirmed using cell-free assays in the presence of glutathione (GSH).

Aside from the targets identified in the cell-free assays above, cell-based assays suggest inhibition of the TIM22 import pathway, the GLP-1 receptor, HSP90, and tyrosyl-DNA phosphodiesterase 1 (see AIDs 493003, 540268, 540270, 624417, 686978 and 686979).