Wilber uses the term "postmodernism" to refer to the rejection of the claim that science is value-free and objective.
If scientists are supposed to be neutral, value-free, and objective, how can they become activists against DT?
But the idea that it will be somehow value-free and objective because it begins with genes instead of behavior is to impose a value on crude reductionism that will not lead to any more objectivity than can be found in the pages of the DSM-5.
Alternative endpoints such as progression-free survival, disease-free survival, and objective response rate have been used to identify benefit earlier, but their true validity as surrogate endpoints is controversial.
We hypothesised that patients with CRFS would have alterations in 24-h urinary free cortisol and objective evidence of decreased physical activity and disrupted sleep (as measured by actigraphy).
When combined with BVZ, progression-free survival and objective response rate in patients with metastatic breast cancer were significantly improved compared to PTX alone [24, 25].
Docetaxel plus bevacizumab combinations have recently been shown to significantly improve progression-free survival and objective response rate compared with docetaxel monotherapy.
In the Iressa Pan-Asia Study (IPASS), EGFR mutations were reported to be the strongest predictive biomarker for progression-free survival and objective response rate to first-line gefitinib versus carboplatin/paclitaxel (Fukuoka et al., 2011).
This study provided examples of significant improvement in progression-free survival and objective response rates with ifosfamide.
There were no statistically significant differences in OS, progression-free survival, and objective response between arms A and B, and between arms C and D, respectively.
