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Additionally, the qRT-PCR method itself is fraught with issues such as loading of reagents, variability between technicians, normalization between samples and choice of housekeeping genes.
A simple morning's greeting and response appear loaded with innuendo and fraught with implications.
It's just another day albeit loaded with anticipation and fraught with peril.
However, the subject is not fraught because "the left" has loaded it with toxic racial politics.
Describing the economy as fraught with uncertainty, she highlighted the huge debt load; the volatility of the equity markets, which are trading two times above the historical average; and feeble consumer confidence.
However, accurately estimating incipient electrical load of rural consumers is fraught with challenges.
Loading your team with players who could play twice is fraught with danger - because of FA Cup semi-finals weekend.
Over the past few years, training load and performance in competition has continuously increased and is fraught with risk to result in the accumulation of fatiguing conditions.
Denial is fraught with peril.
Fraught with danger and disappointment?
Innovation, by definition, is fraught with risk.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com