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The development of novel neuroprotective treatments for acute stroke has been fraught with failures, which supports the view of ischemic brain damage as a highly complex multifactorial process.
The Humane Society of the United States and the American Anti-Vivisection Society blasted BioArts in a press release, calling pet cloning "a bizarre scientific endeavor fraught with failures and animal suffering".
Drug development for obesity has been fraught with failures and false-starts, in part owing to the complex pathways that govern energy homeostasis.
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The design of any device, machine or system is fraught with failure.
For every moment of success, it seems fraught with failure and disappointment.
There's a phrase that has haunted America for decades, one fraught with failure: "Breaking the cycle of poverty".
The response from the private sector today isn't new, either: In the early 1900s, consolidated power companies claimed that public ownership of electrical utilities was "costly and dangerous" and fraught with failure.
Innovation is fraught with failure, and if a product line fails, the company would like to isolate the failure so the negative side effects do not spill over to its other products.
All in all the experience of oral VEGFR TKIs in colon cancer has been fraught with failure; after all, these drugs are pharmacologically and pharmacodynamically inferior.
The history of adjunctive treatments for severe sepsis has been fraught with more failures than successes.
Each case is fraught with massive failures in our justice system, and as a result victims have been locked up for decades.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.
Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com