The generation of a complete and annotated genome sequence establishes the genetic infrastructure for such studies, provides a framework to organize all the genetic information about the organism, and catalyzes future 'omics' research.
The objectives of this paper are first to show the limits of such an organization, and second to provide a heuristic framework to organize the design of coupled innovations, by reconnecting the dynamics of innovation in agriculture and food, with a view to improving the whole agrifood system.
The paper concludes with a call for a framework to organize and understand the myriad of financial disclosure style choices made by firm management.
The ongoing work within the ScalaLife programme should help the community move in this direction, while the data model presented here will provide a good framework to organize, describe, and index computational experiments comprising multiple tasks.
Here, we describe Onco-GPS (OncoGenic Positioning System), a data-driven analysis framework to organize individual tumor samples with shared oncogenic alterations onto a reference map defined by their underlying cellular states.
Thus, variation in riparian plant community characteristics can be explained using a nested, hierarchical landscape framework to organize and group different riparian settings based on the underlying geomorphic processes shaping stream valleys.
It brought concepts related to plant evolution into line with animal evolution as it emerged from Dobzhansky's 1937 Genetics and the Origin of Species and provided the conceptual framework to organize a disparate set of disciplines into a new field: plant evolutionary biology.
Connecting viral variants that differ in one mutation provides a natural framework to organize the heterogeneous population of viral variants.
Using this framework to organize the data guided analysis within each practice as well as between practices.
Metabolic reconstructions constitute a framework to organize genomic, proteomic, metabolomic, and other data sets and to assess the effects of perturbations on these elements at the network level.
