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In this paper, we have developed an integrated multiscale modeling framework to decipher the impact of non-synonymous Single Nucleotide Polymorphisms (nsSNPs) on the information flow from the activity of a single molecular component, to the function of the complete molecular machinery, and ultimately to the emergent properties of the biological network.
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BayMiR applies a more relevant biological model and uses a large collection gene expression data to decipher the impact of miRNAs on gene expression data.
The representation of GPCR structures as networks of interacting amino acids can be a meaningful way to decipher the impact of ligand and of dimerization/oligomerization on the molecular communication intrinsic to the protein fold.
Therefore, in future studies we want to further optimize Ca2+-transport measurements in liposomes and intent to decipher the impact of divalent cations on AtAPC1-3 functinn in vivo.
The reference genome assembly OryCun2.0 (AAGW00000000.2, http://www.ncbi.nlm.nih.gov/genome/ term=oryctolagus%20cuniculus) has provided insights to decipher the impact of the domestication process on shaping genomes [ 7].
Species and phyla that originated in periods of massive genetic changes provide attractive experimental frameworks to decipher the mechanisms of emergence and stabilization of phenotypic innovations.
If the regressors are correlated, the BLUE property of the model holds but, it becomes difficult to decipher the distinct impact of each of the covariates on the regressand.
Decades after weapons testing stopped, researchers are still struggling to decipher the health impacts of radiation exposure around Semipalatinsk. Wudan Yan is a journalist in Seattle, Washington.
We compare the fire history data with a regional biomass-burning reconstruction from 18 different charcoal records and with pollen, climate, and population data to decipher the relative impacts of regional climate, vegetation changes, and human activity on fire.
It's been hard to decipher the broader impacts of technology on the average San Franciscan because heart string-tugging anecdotes have clouded the narrative.
The challenge with architectural complex successions, like those on the Cayman Islands, is that of deciphering the impact of sea-level changes as opposed to tectonic influences.
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