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The current review covers recent translational approaches to bridge the gap between human and animal PTSD research and to create a framework for discovery of biomarkers and novel therapeutics.
These results provide a biological framework for discovery of potential target genes, such as Creb3l4, in obesity treatment.
The advent of genome-wide SNP arrays and imputation-based meta-analysis has provided a robust statistical framework for discovery and replication, and boosted locus discovery revealing a wealth of genetic loci associated with disease and quantitative end points.
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Overall, we know that p-values have a variety of weaknesses when being used in scientific reasoning [ 11, 12], and we should recognize these limitations by reinforcing our frameworks for discovery and validation.
This paper presents a generic framework for knowledge discovery in massive BAS data using DM techniques.
Our research attempts to create a computational framework for the discovery of co-occurring diseases, medications, and symptoms in COPD patients.
It may form a basis for shikonin optimization through twin drug design framework for the discovery of new and potent shikonin derivatives in the study of targeted cancer therapy.
As faculty seek to adjust to the demands of CBE, van Merrienboer's 4C-ID methodology provides a framework for the discovery of the authentic tasks performed by experts in real-world settings.
However, the key difference is TargetMine's flexibility and its built-in prioritisation protocol; the data size and data types are readily customisable in TargetMine, providing a more flexible and comprehensive framework for target discovery.
This work provides the essential mechanistic framework for drug discovery.
We provide a framework for gene discovery and functional investigation of HMs in other Solanaceae species.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com