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The CACE (ie, the effect of treatment in participants compliant with allocation) was to reduce frailty by 1.0 frailty criterion (95% CI 0.4 to 1.5) and increase mobility by 3.2 points (95% CI 1.8 to 4.6) at 12 months.
The frailty criterion was modified from previous studies.
In addition those with obesity were more likely to meet the reduced physical activity frailty criterion.
The frailty criterion most prevalent among frail individuals was slow walking speed (75.7%) and fatigue among the pre-frail (29.6%).
Almost 51%% had visited their general practitioner during the previous two months, and nearly two-thirds visited a medical specialist over the previous twelve months.> Figure 1 shows the prevalence of each frailty criterion.
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Original Fried's frailty criteria have not demonstrated their prognostic validity of mortality, disability and mobility loss in European cohorts.
The mean CACE was substantially larger than the intention-to-treat effect, which was to reduce frailty by 0.4 frailty criteria (95% CI 0.1 to 0.7) and increase mobility by 1.4 points (95% CI 0.8 to 2.1) at 12 months.
The purpose of this study was to assess the additive value of cognitive function with existing frailty criteria to predict poor postoperative outcomes in a large multidisciplinary cohort of patients undergoing major operations.
The purpose of this study was to critically analyze the components of the Fried Frailty Criteria, among other preoperative variables, to create a simplified risk assessment amenable to a busy clinical setting, while maintaining prognostic ability for surgical outcomes.
The analyses of the constructs of frailty and depression were investigated from three perspectives, namely, the relationships: 1) between frailty criteria and depression prevalence; 2) between frailty profiles and depression prevalence; and 3) of specific symptoms of depression with specific criteria of frailty.
The results suggested that frail elderly had a self-perception of being less healthy, increasing the chances of negative feelings and cognitions about themselves and others; as well as changes in appetite and weight, which overlapped with the frailty criteria.
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