Finally, this ARDS situation is clinically plausible in these frail lung's patients with established predisposition to infections [ 19], cancer chemotherapy and G-CSF-induced pulmonary toxicity, and sometimes to pulmonary infiltration by the malignancy.
Jinnah did what he could for the eight million people who migrated to Pakistan; although by now over 70 and frail from lung ailments, he travelled across West Pakistan and personally supervised the provision of aid.
The BBC's Andrew Harding in Johannesburg says news that the frail Mr Mandela has another lung infection is likely to generate considerable anxiety.
The poorly understood disease trajectory of the frail elderly echoes recent understanding of accelerated lung ageing in smokers, 41 and the biomedical model of decline in lung function, 39 and may resonate best with the disease trajectory of COPD.
The higher percentages in the two latter studies may be partly explained by the inclusion of patients with unconfirmed lung cancer and probably too frail to undergo diagnostic procedures.
We had vanquished the threat, and now, once more, we faced the object of our efforts, a creature so frail that even the labor of its own lungs seemed too much for it.
The little boy had also been diagnosed with cystic fibrosis, a genetic disorder that mostly affects the lungs, and his body was so frail, he struggled to breathe.
For example, consider a frail, elderly, atherosclerotic patient who now develops a lung infection.
Lung cancer patients are often symptomatic, frail or elderly and participation in a molecular imaging study is associated with the burden of additional scans without a potential therapeutic benefit.
Hard to reach and an unhelpful shape, opening up a patient's chest has been the only way to solve the problem, putting it beyond the reach of hundreds of people considered too high-risk because they are frail (usually elderly) or have complicating problems such as lung disease.
