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"You can't give this drug to older, frail individuals, and you shouldn't," he said.
The deaths caused by the virus were not from simple exhaustion in frail individuals.
Frail individuals are at increased risk for poor outcomes, including adverse drug events.
The identification of frail individuals has been recognized as a priority for the effective implementation of healthy aging strategies.
The longitudinal analysis also revealed that pre-frail and frail individuals were more prone to presenting new and persistent depressive symptoms at follow-ups than non-frail individuals.
Hospitalized, frail individuals aged 65 and older were randomized to receive care in a geriatric inpatient unit, a geriatric outpatient clinic, both, or neither.
The higher power of the DI for discriminating frail individuals in their susceptibility to death also followed from comparison of quasi-instantaneous values of both indices.
A disproportionate number of frail individuals (7/141, 5%) possessed the minor allele (C) at this position compared to the non-frail individuals (0/151).
The non-pilot white participant group includes few frail individuals however adjusted models still indicated a small positive association between the C allele and frailty (Table 3).
Self-reported frail individuals were slightly older than non-frail individuals.
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However, the prevalence of depression is greater among frail than non-frail individuals, and differs significantly from those not presenting these conditions.
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