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It is important to note that these guidelines are predominantly applicable only to elderly patients who are fit, rather than those who are less fit or frail, due to the scarcity of data relating to treatment of this latter group.
7 Older individuals, relatively frail due to their susceptibility to both cerebrovascular disease and to new onset seizure disorder, require that safe medications for seizure control be utilized to treat their disorders.
The Caucasian patients could be more frail due to a variety of comorbid conditions (i.e., osteoporosis, weight loss or low BMI, cellulitis or decubitus ulcers, fluid electrolyte imbalances, anemia, age >80, syncope, nursing home residence).
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Concerns included Jackson's frail appearance due to lack of eating that had reportedly caused Jackson to be unable to perform from lack of strength and that AEG had used body doubles in rehearsals to stand in for Jackson.
However, high-dose chemotherapy and autologous stem cell transplant are not suitable for elderly frail patients due to significant toxicities.
Associations between capabilities, health and well-being may be weaker in a general sample of frail elderly due to less variation in measurements.
The issue has thus raised health policy interest in Sweden, but mostly focussing on one of the causal factors behind elderly injuries; osteoporosis (frail bones due to low bone mass).
Furthermore, the 22 45% risk of pneumothorax after transthoracic marker placement may be unacceptably high for some of this generally frail patient population due to severe cardio-pulmonary co-morbidity [ 8, 11– 13].
Patients were also significantly more likely to have received lifestyle interventions when providers considered it to be 'appropriate' compared to patients where it was considered inappropriate because of extrinsic patient or service factors such as the patient being of frail age or due to a lack of time (OR = 25.89, CI = 4.78 140.26, Model 2).
The Danish Technology Council claims that in the future the elderly population will be polarised into a large group of healthy elderly and a large group of frail elderly who due to medical improvements may live with chronic diseases in more years than previously observed [ 2].
Others, including a still-frail Citigroup, were due to report after The Economist went to press (see article).
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