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However, multiple rearrangements occurring outside of gene clusters resulted in the fragmentation of alignment units between genomes.
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This is manifested by the continuous presence of indels, ranging from a few kb up to several tens of kb, which cause fragmentation of the alignment patterns (Additional file 5: Figure S4).
6 gene families were removed because of difficulty in generating a reliable alignment, fragmentation of the gene in CPXV, or excessive computational time required for analysis due to large family size and length of genes.
This algorithm allows the systematic fragmentation of metabolic pathways for the alignment analysis, and it has been used to identify the shortest pathway between compounds in metabolic networks [ 21].
To address the fragmentation of care currently provided (in alignment with the PCEHR), a maternity EHR has been developed and is currently being trialed in a general practice (GP) shared-care setting.
This issue and its implications for country ownership of donor programs and aid alignment was one of the catalytic factors behind the development of the IHP+ with its emphasis on reciprocal accountability, reducing the fragmentation of aid for health, and promoting alignment with country priorities [ 62].
Or out of alignment".
"I'm all out of alignment".
"Well out of alignment there," he pronounces.
Also, high winds can knock the dishes out of alignment.
Something is out of alignment, to be sure.
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