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To determine the meiotic segregation and DNA fragmentation in spermatozoa of carriers of a chromosomal structural abnormality.
Objective: To determine the degree of DNA fragmentation in spermatozoa of men with obstructive azoospermia or anejaculation compared with that of ejaculated spermatozoa from fertile donors.
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To evaluate DNA fragmentation in spermatozoa with normal morphological appearance.
Many reports suggests that high levels of reactive oxygen species cause the DNA fragmentation commonly observed in the spermatozoa of infertile men [ 41– 41].
The InsGs were particularly frequent in spermatozoa, irrespective of exposure.
Varicocele is associated with high levels of DNA damage in spermatozoa due to oxidative stress and elevated levels of sperm DNA fragmentation, which has been currently proposed to be an essential additional diagnostic test to be recommended for patients with clinical varicocele.
As a result, we found that GO is able to interact with spermatozoa membranes and, in particular, it seems to be able to extract the cholesterol, which is a key player in spermatozoa physiology, from plasma membrane of boar spermatozoa incubated under capacitation conditions.
In spermatozoa from TZ patients, only 2out of 16 CpGs were significantly hypomethylated.
From our analysis, HPV presence in spermatozoa may be associated with an impairment of sperm parameters.
Their retention in spermatozoa begins to occur during early stages of spermatogenesis.
In contrast, frozen-thawed spermatozoa of low viability had significantly higher velocity values than fresh spermatozoa of low viability.
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