Sentence examples for fragmentation in nuclei of from inspiring English sources

To detect apoptotic cell death in individual cells, primary neurons and glial cells were fixed with 3% formaldehyde in PBS and DNA fragmentation in nuclei of cells in apoptosis was stained by use of a TUNEL detection assay.

DAPI staining performed to analyze morphological changes showed DNA fragmentation and an unusual change in nuclei of HT29 cells, an early apoptosis phenomenon probably, after treatment with IC50 value of SN38-PEG-PLGA-Ver nanoparticles.

The transient decrease in the CAT expression co-occurred with slight DNA fragmentation in the nuclei of megagametophyte cells – that is to say, an incipient sign of cell death – detected in our previous study [ 35].

Third, AVO caused DNA laddering and fragmentation in apoptotic nuclei of HL-60 cells, a well-recognized process typically occurring during apoptosis [ 49].

TUNEL staining showed DNA fragmentation in the nuclei of such astrocytes and TUNEL-positive DNA was also diffusely dispersed within the cytoplasm, a pattern characteristic for cell necrosis (Fig.  1n).

In addition, regucalcin may suppresse effect of Ca2+ on DNA fragmentation in the nucleus of H4-II-E cells.

A TUNEL (dUTP nick end labelling) assay for the detection of DNA fragmentation in apoptotic nuclei was performed on the paraffin sections of six MDA/EGFP and six MDA/RLN2 nude mouse tumours using the TACS.XL In situ Apoptosis Detection Kit (Trevigen Inc, Gaithersburg, MD, USA) according to the manufacturer's instructions.

Apoptotic cells were identified by transport of phosphatidylserine to the membrane surface and by microscopic observation of DNA fragmentation in the nucleus.

Interestingly, this followed the DNA fragmentation in the nucleus which is a late apoptotic event (data not shown).

Apoptotic cells were identified by condensation and fragmentation of the nuclei (separated nuclei composed by clusters of blue dots).

As shown in Fig. 4, small holes appeared in the nuclei of treated cells, and DNA fragmentation was clearly evident.