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As a coalition of more than 1,000 soup kitchens and food pantries, we have seen these fragile programs, originally started to provide emergency help, become the front-line social service system for more than half a million New Yorkers.
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Using gene expression profiles under normal growth condition [ 17- 19], we found that cooperative TFs in the robust transcriptional regulatory program are significantly more co-expressed than those in the fragile program (P < 10-18, Mann-Whitney U-test; Figure 1A).
Barriers to including these vaccines in routine immunization schedule in India include potential negative impacts on fragile existing immunization programs and cost.
We have investigated into the cause and effect of robust and fragile transcriptional regulatory programs.
We have analyzed robust and fragile transcriptional regulatory programs in terms of their TFs, and next would turn our analysis to robust or fragile genes (i.e. genes with robust or fragile transcriptional regulatory program).
If a given TF is involved in fragile transcriptional regulatory programs, the expression of its cohort genes should be significantly affected by its knockout.
We have demonstrated that genes with fragile transcriptional regulatory programs under normal growth condition tend to participate in ESR, though the number of TFs that bind them in stress conditions is comparable with that of robust genes.
At all three sites a research assistant reviewed the newborn nursery admittance record daily, approached parents to obtain consent for the newborn to participate in the fragile X screening program, which was separate from the state newborn screening programs.
We referred to TFs involved in robust or fragile transcriptional regulatory program as robust or fragile TFs, and referred to genes having robust or fragile transcriptional regulatory program as robust or fragile genes.
These warriors, hobbled by injuries and psychologically fragile, enter a program that treats the guy's-guy pastime of fly-fishing as regenerative meditation.
Usually, that means performing those tasks a safe distance away from the fragile humans that programmed them.
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