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As the flap is fragile, damage to the vascular pedicle may result in graft loss.
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The result is that you are taken deep into a fragile, damaged yet somehow rationally irrational psyche.
The DNA that holds the genetic information inside cells spends most of its time wrapped around proteins called histones: this allows the DNA molecules which can be up to several metres long in some species to fit inside the cell nucleus; it also protects the DNA molecules, which are quite fragile, from damage.
The Jemima that gradually emerges from these pages is fragile and damaged.
"It seemed to be a call to arms for the fragile and damaged of the world," he said.
Above all, it threatens China's economic renaissance, already looking more fragile, by damaging relations with the US and putting investors off the whole region; and the Chinese resent their citizens being exposed to radiation.
Earlier in the week Mr Wen's ambassador to the country, Zhang Yan, said bluntly at a public meeting in Delhi that bilateral ties were important but "very fragile", easily damaged and "difficult to repair".
The active metabolites of PAH may lead to defects that indirectly induce cell death in fragile and damaged mature sperm.
But there are concerns that the proposed mines will harm fragile ecosystems, and damage the traditional Inuit fishing and hunting trades.
"No recreational mowing," says Rossi, because the vibrating wheels of your lawnmower can damage fragile turfgrass crowns.
Importing them is complicated because of government regulations meant to protect endangered birds, and shocks in transit can damage fragile quills.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com