Sentence examples for fractionated administration from inspiring English sources

In their modelling study, Cremonesi et al. showed that liver tissue might be spared by fractionated administration of microspheres [13].

Further long-term studies on mice are ongoing not only to validate if RBP4 may be efficient in predicting late renal toxicity at lower absorbed doses and for fractionated administration but also to investigate other biomarkers of proximal tubular and glomerular damage in serum and urine.

In conclusion, fractionated administration of CPT-11 and CDDP was highly effective for advanced NSCLC with manageable toxicities.

Therefore, the fractionated administration of paclitaxel and gemcitabine on the same days apparently increased the therapeutic index of the combination, supporting its use in elderly patients.

A phase II study of fractionated administration of irinotecan (CPT-11) and cisplatin (CDDP) in patients with non-small-cell lung cancer (NSCLC) was conducted.

We conducted a phase I study to investigate whether the fractionated administration of CDDP and CPT-11 at escalated dose was feasible and could improve the treatment outcome.

Cures were seen in five out of six animals receiving the single fraction therapy and two out of six animals receiving a bi-fractionated administration, whereas no cures were seen in either the three or four fraction groups.

Furthermore, fractionated drug administration may increase chemotherapy dose intensity.

As the question of whether fractionated CPT-11 is more effective than CPT-11 given as a single dose on day 1 cannot be assessed from a phase II study, a randomised study comparing fractionated vs 1-day administration of CPT-11 with 5FU/LV is shortly planned to clarify this issue.

A recent study [ 18] had suggested their highly fractionated protocol allowed the safe administration of a higher cumulative dose of drug and was part of the reason why they saw a notable benefit for GO in their trial.

The vaccine was further fractionated four times, and the last administration was six-tenths of the dose.