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In a statement for this article, it questioned the study's methodology, noting that it considered only papers with abstracts, which are included in a small fraction of studies published in each issue.
Only a fraction of studies presented data on subgroups.
First it appears when we report the fraction of studies that tested a dose response.
Encouragingly, a large fraction of studies reported tissue location, procurement method, and discussion of PD results.
Similarly, the fraction of studies that examined rehabilitative care is small and has remained stable over the past 14 years.
A large fraction of studies were conducted among different clinical populations (Table S3 of Additional file 1).
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Only a small fraction of study participants trusted manufacturers and authorities (Fig. 2).
A modest fraction of study participants displayed CLCR measures significantly higher than might be expected, a finding that requires further evaluation.
Although many studies report the age and sex of the study subjects, only a fraction of these studies were able to establish a statistically significant effect by gender [ 42, 43] or by age [ 44– 44].
Figure 1(c) shows that with a model without a treatment effect the fraction of negative studies was never below 5% for all studies while with a model with treatment effect it was below 5% for all cases.
We further take the fact that a large fraction of PD studies were described as informing decisions for future studies as support for invasive PD evaluation.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com