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The same investigators demonstrated that intrapericardial infusion of galectin-3 into healthy rats increased left ventricle collagen density and reduced ejection fraction of left ventricle for 22%.
In previous studies comparing patients with AF and sinus rhythm, the mean ejection fraction of left ventricle was lower than that in our study.
ACS - Acute coronary syndrome, ADHF - Acute decompensated heart failure, PCI - percutaneous coronary intervention, EF LV - Ejection fraction of left ventricle.
Subjects with impaired systolic function (ejection fraction of left ventricle < 50%) or history of coronary artery disease were excluded.
Cardiac echography showed normal chamber size, normal LV segmental wall motion without significant valvular defect and the ejection fraction of left ventricle was about 60%%.
The levels of ROS as well as HNE, an end-product of lipid peroxidation, evaluated in cytosolic fraction of left ventricular tissue, increased significantly in untreated diabetic rats (Table 3).
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Recent studies revealed changes in gene expression and in the contents of beta-actin, gamma-actin, alpha-actinin-1 and 4 in membranous, and cytoplasmic protein fractions of left ventricle cardiomyocytes of mice after being exposed to a 30-day space flight onboard the BION-M1 biosatellite [ 27].
Conventional parameters (ejection fraction of the left ventricle (LVEF), left ventricular end-diastolic diameter (LVEDD), left ventricular end-systolic diameter (LVESD), septum wall thickness (SWT) and posterior wall thickness (PWT)) were measured in M-mode recordings at the level of the papillary muscles.
One experienced observer (>5 years in Cardiac MR and CT) blindly and randomly analyzed all MR and CT images to measure the end-diastolic volume (EDV) and end-systolic volume (ESV), and calculate the stroke volume (SV) and ejection fraction (EF) of left and right ventricle, as well as the end-diastolic wall mass (ED Wall Mass) on the left ventricle.
A qualitative eyeballing evaluation of the ejection fraction of the left ventricle (LV) was adopted[22].
Depressed ejection fraction of the left ventricle (<50%) Minor criteria a.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com