Sentence examples for fraction of altered from inspiring English sources

Adding KRAS to this set increases the fraction of altered samples to 49%.

Thus, a large fraction of altered genes by FUS/TLS depletion were dependent on CNS regions.

Hence, they provide a limited analysis of pathway activity that is based on the small non-representative fraction of altered genes that are currently annotated in pathway databases.

The comprehensive gene expression profiles of each cell type composing normal breast tissue and breast carcinomas demonstrates that extensive gene expression changes occur in all cell types during cancer progression and that a significant fraction of altered genes encode secreted proteins and receptors (Allinen et al. 2004).

The fraction of altered mitochondria, defined as number of mitochondria with disrupted cristae divided by total number of mitochondria in a view, was calculated.

On a genome-wide basis, the overall fraction of altered loci was not significantly different between primary tumors and metastases.

Similar tendencies were observed when using 3 different metrics to assess genomic instability (total size of the genome altered, fraction of probes altered, or number of altered segments identified; see methods section).

To gain a more accurate assessment of the relationship of STAG2 mutation with genomic instability, we tested the relationship of mutation with genome-wide copy number alterations measured as fraction of genome altered (FGA; percentage of clones on the array that reported significantly altered copy number).

The size in base pairs (bp) of the segmented regions altered (lost or gained) was calculated from the start and end position of the segments; (2) fraction of probes altered - proportion of probes showing loss, gain, and amplification; (3) number of altered segments identified - the total number of individual altered segments, lost or gained, was determined from the waviCGH segmented call data.

We also evaluated the simultaneous effect of total number of alters (whether happy or unhappy) and the fraction of alters who are happy.

However, considering the different genetic background and cancer cell lines in the two mouse modes, it is not surprised that only a fraction of total altered genes was overlapped (4.8% (11/225) or 3.8% (11/290) up-regulated genes in melanoma model or lung cancer model, respectively; 4.2% (17/403) or 2.1% (17/784) down-regulated transcripts in the two models, respectively).