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Since we're giving away three free spots to top founders in each featured pavilion, it makes sense to do the same for the investors who have chops in the relevant field.
The founders in each pedigree were assumed to be unrelated.
The method is briefly outlined as follows: founders in each family are selected to form an unrelated sample on which principal component analysis is performed with available genotype data.
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In the US, Y Combinator invests $11,000 + $3000 per founder in each startup and gets back 6 or 7% in stock options.
Principal components for non-founders in each family are inferred according to those for their founder relatives through a TDT strategy.
Founder, In-Deep.
But we have precious few institutions reminding us to join the Founders in pledging something to each other.
Using a software program called BOTTLENECK, the two searched for the signature of bottlenecks or founder effects in each population to see if the loss of diversity occurred suddenly or gradually as adjacent populations moved farther from Africa.
Second, we limited the HapMap 3 analysis to only 100 founder chromosomes in each of the populations to ensure identical precision in the allele frequency estimates of the respective populations.
Because the test is performed under a null permutation distribution which conditions on the set of founder haplotypes in each nucleus, it is robust to population stratification differences between nuclei.
In embryos, lms is expressed specifically in the four lateral transverse (LT) muscles and their founder cells in each hemisegment, whereas in larval wing imaginal discs, it is expressed in myoblasts that develop into direct flight muscles (DFMs), which are important for proper wing positioning.
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