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As a foundation for structures, earth must be dry and firm.
CPT provides data for estimating engineering properties of soil which intended to help with the design and construction of earthworks, foundation for structures, and the behaviour of soils under static and dynamic loads.
As a base for design, earth is the floor of landscape spaces, the root medium in which half of every plant lives, the foundation for structures, the vehicle for surface and subsurface drainage of excess water, and a sculptural material in its own right.
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The structural information provides a foundation for structure-based design of new inhibitors against these enzymes.
The co-crystal structure describes a structural basis for interaction and provides a firm foundation for structure-assisted design of lead compounds with appropriate molecular properties for future drug development.
Detailed information on the active site of PMM/PGM lays the foundation for structure-based inhibitor design.
The bacterial NaMN adenylyltransferase structures described here provide a foundation for structure-based design of specific inhibitors that may have therapeutic potential.
Structures of over 30 different G-protein-coupled receptors (GPCRs) have advanced our understanding of cell signaling and have provided a foundation for structure-guided drug design.
Accurate and rational determination of explosion loading on tanks is the foundation for structure damage analysis and explosion resistance design of tanks.
The recently determined X-ray crystal structures of AKR1C1/NADP+/20α-hydroxyprogesterone AKR1C1/NADP+/20α-hydroxyprogesteroneic andd ternAKR1C1/NADP+/3,5-dichlorosalicylic AKR1C1/NADP+/3,5-dichlorosalicylicesign methods to improve inhibitor selectivity acidpoternary
These results lay the foundation for structure determination of E1-TM and a molecular understanding of how E1-TM flexibility enhances its interaction with E2-TM during heterodimerization and membrane fusion.
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