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The chiral selectivity of this enzyme was investigated by molecular docking and site-specific mutagenesis, which provides a foundation for further engineering of these versatile biocatalysts.
Our present study provides an experimental foundation for further engineering exploitation research on the three-phase methanol synthesis process with supercritical medium in three-phase slurry reactors.
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Taken together, all the above knowledge laid a foundation for understanding the unique cellulase system of P. oxalicum and provided novel targets for further engineering of P. oxalicum and other industrial producers.
These results provide a solid foundation for further metabolic engineering of S. zooepidemicus for highly efficient HA production.
By producing ethanol at 75 °C, this work lays the foundations for further metabolic engineering and process optimization that could lead to in situ ethanol removal during fermentation to enhance recovery and decrease product toxicity.
The efficient and accurate stiffness measurement has been considered as the foundation for further development of railway engineering, and therefore has great theoretical and practical significance.
Test results also show that the new embedded sensors have very good mechanical-electrical coupling performance, which builds a solid foundation for further application in the civil engineering infrastructures.
This is the first report presenting the microbial coproduction of MCL-PHAs and CdS QDots in P. putida KT2440, thus constituting a foundation for further bioprocess developments and strain engineering towards the efficient synthesis of these highly relevant bioproducts for nanotechnology.
The clinical success with first- through third-generation ACI in patient populations with very symptomatic and challenging cartilage lesions has laid the foundation for further progress in cell-based orthopedic tissue engineering in general and cartilage repair in particular.
The findings form a foundation for further understanding the specificity of trans-AT ACP protrans-AT ACPtions and for engineering modular proteininteractionss to produce andlogs.
Together these results expand the utility of CRISPR/Cas9-mediated genome engineering in human cells and provide a foundation for further advances using Cas9 RNP delivery methods.
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