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In human THP-1 cells, these compounds were found to upregulate the expression of the surrogate cellular biomarker CD86.
In addition to VEGF-A, PMA and A23187 were also found to upregulate the expression of RCAN1.4.
On the other hand, females were found to upregulate the expression of HSP70 in response to S. entomophila.
15d-PGJ2 has been found to upregulate the expression of PPAR-γ and also the DNA binding and transcriptional activity.
More recently, proteasome inhibitors have also been found to upregulate the expression of BCL-2 family proteins.
In addition, MdCIbHLH1 was found to upregulate the expression of MdCBF1, MdCBF2, MdCBF3, MdCBF4 and MdCBF5, further confirming that MdCIbHLH1 works upstream of the MdCBFs.
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Translational regulatory RNA (treRNA) was found to function in the nucleus as a cis element to upregulate the expression of Snail while suppress cytoplasmic E-cadherin expression promoting EMT in cancer cells [126],[126].
Inhibition of MEK was found to upregulate Bim expression in both cell lines and to sensitize SW620 cells to anoikis.
To cope with low temperatures, plants often upregulate the expression of some cold related genes (CORs).
Similarly, we found that lithium upregulated the expression of the endogenous caspase inhibitor XIAP.
We found that EGF upregulated the expression of SBSN in NEC.
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