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Finally, TSG was found to suppress the expression of cytochrome P450 2E1 (CYP2E1) and the phosphorylation of c-jun terminal kinase (JNK) in NAFLD mice.
Both SG1 and TSG were found to suppress the expression of cytochrome P450 2E1 (CYP2E1) and the phosphorylation of c-jun terminal kinase (JNK) and its downstream target c-Jun in OA-treated cell.
For example, BART2-5p miRNA has been shown to inhibit EBV lytic replication by targeting the viral DNA polymerase BALF5 [12], while BART1-5p, Band16-5p and BART17-5p have been found to suppress the expression of the viral oncoprotein LMP1 [13].
Insulin is found to suppress the expression of TLR2 in mononuclear cells at the transcriptional level [ 19].
let-7 was found to suppress the expression of Ras, c-myc, E2F1, and CDC34, as well as to elevate the expression of p21.
The expression of nAG in human fibroblasts was found to suppress the expression of collagen with or without transforming growth factor-beta1 (TGF- β1) stimulation [ 10].
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Furthermore, intraperitoneal administration of these expression plasmids was found to suppress the peritoneal dissemination of implanted pancreatic cancer cells.
Furthermore, we used specific PI3K inhibitor to suppress the expression of PI3K, and found that the expression of C-Jun and C-Myc was reduced accordingly.
In addition, LPS exposure has been found to suppress mRNA expression levels of different clock genes, in both animal [25] and human studies [26, 27].
The expression of nAG in human primary fibroblasts was found to suppress collagen expression.
20 Sirtuin 6 has been found to suppress aerobic glycolysis by influencing the expression and function of HIF-1α.
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