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In addition, OsWOX3 has been found to repress the expression of OsYAB3, which is required for cell differentiation during rice leaf development (Dai et al.2007).2007
The ESCC MiRNAs have been found to repress the expression of methyl CpG binding protein MBD2; and knocking down MBD2 can increase the efficiency of reprogramming (Subramanyam et al., 2011; Lee et al., 2013).
More recently, miR-181b was found to repress the expression of importin-α3, which is required for the nuclear import of NF-κB proteins (Sun et al, 2012).
Furthermore the three herbs were found to repress the expression of the iNOS gene, which is considered to be an important damaging factor during hypoxia/ischemia [ 37].
MicroRNAs like miR-29a and miR-32 have been found to repress the expression of viral mRNAs by possible recognition and targeting of viral nucleic acids with miR-29 specifically targeting HIV-1 3'UTR region [ 11], [ 12].
The first animal miRNA, lin-4, was discovered during a genetic screen in Caenorhabditis elegans (C. elegans) and was found to repress the expression of the protein-coding gene lin-14.
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First discovered in bacteria as part of an adaptive immune system, CRISPR/Cas9 and modified versions have found a widespread use to engineer genomes and to activate or to repress the expression of genes.
For all types, except HPV-18, the region was found to repress expression by posttranscriptional mechanisms.
Consistent with its expression profile, RBf2 was found to repress differentiation markers in embryos and ovaries.
However, the authors found that these miRNAs repress the expression of pluripotency factors by binding to their coding regions.
Furthermore, we have found that CLF, EMF2 and FIE also repress the expression of MAF4 and MAF5.
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