The Taxus chinensis WRKY1 was found to regulate the expression of 10-DEACETYLBACCATIN III-10 B-O-ACETYL TRANSFERASE (DBAT), a gene encoding a key enzyme catalyzing a rate limiting step in the biosynthesis of the anticancer terpene, paclitaxel [ 47].
Furthermore, the violent side-effects associated with the clearance of cancer cells make it desirable to find ways to regulate the rate of CTL activation.
Thus, the possibility exists to regulate the rate of drug release from the cubic phase.
SIRT2 was found to regulate adipocyte differentiation through inhibition of PPARγ.
They were found to regulate viscoelastic properties and motility of cancer cells.
Alternatively, the levels of Cdk8 itself may be rate-limiting as overexpression of Cdk8 has been found to regulate β-catenin levels in colorectal cancers [4].
Also, rearrangements of Rad51 filaments and their association with Brca2 were found to regulate homologous recombination.
Nor do they regulate the rate of release, thus subjecting rivers and their inhabitants to harmful fluctuations in water levels and temperatures.
In addition, CYLD is found in the midbody where it also associates with HDAC6 and regulates the rate of cytokinesis.
The other gene regulating the rate of spikelet formation – LOG, had a high expression in all the developmental stages analyzed and interestingly, we found a negative correlation between the expression patterns of both these genes (Figure2B).
