Sentence examples for found to inhibit the motility of from inspiring English sources
Re-expression of PTEN in mammalian cells lacking the enzyme has been found to inhibit the motility of several lineages of such cells, including mouse embryo fibroblasts and tumor-derived cells of glial and prostate origin [8], [27], [28], although most of these studies have not addressed the mechanism of action of PTEN.
Cluster-of-differentiation antigen 9 (also called MRP1) was identified as the antigen binding to the mAb M31-15, antigengen found to inhibit the motility of various cancer cell lines (Miyake et al, 1991).
Re-expression of PTEN in mammalian cells lacking the enzyme has been found to inhibit the motility of several lineages of such cells, including mouse embryo fibroblasts and tumor-derived cells of glial, prostate, and T cell origin [6, 8, 17, 18], although most of these studies have not addressed the mechanism of action of PTEN.
In human spermatozoa, gossypol was shown to inhibit the motility of sperm cells through a dose dependent mechanism [ 32].
Interestingly, in several human normal and neoplastic cell lines, including MDA-MB-468 breast cancer cells, impairment of mTOR pathway by rapamycin was found to inhibit cell motility or invasion (Zhou and Huang, 2011).
Glutamate receptor antagonists were found to inhibit proliferation and motility and increase cell death in lung carcinomas and a variety of other cancers, and glutamate antagonists enhanced the effects of cytotoxic drugs (Rzeski et al, 2002).
Dexmedetomidine was also found to inhibit gastric, small bowel, and colonic motility [ 47].
Genistein and tyrphostin (an EGFR inhibitor) were both found to preferentially inhibit the motility and growth of bladder carcinoma cell lines that overexpressed EGFR (Theodorescu et al, 1998).
Rhosin was evaluated in vitro in a variety of cancer cell models, including physiological three-dimensional mammospheres, and was found to readily inhibit the motility and invasiveness of breast cancer cells in a dose-dependent manner (Shang et al., 2012).
Epidermal growth factor receptor inhibition strongly inhibited the motility of CA125/MUC16 knockdown cells.
Furthermore, truncated ATM1 inhibited the motility of associated ARA6 labeled organelles but could be found on motile FYVE labeled organelles.
