Sentence examples for found to downregulate the expression of from inspiring English sources

Finally, the β-catenin/TGF/LEF complex is found to downregulate the expression of p16INK4a (suggesting another mechanism for p16 downregulation apart from methylation), as well as of miR-15a/16 miR-15a/16 in both furesultingegulatinn of cyclin D1 and increased angiogenesis in MM.

The Nsp2-targeted siRNA was found to downregulate the expression of Nsp2 in MARC-145 cells and inducing replication reduce of PRRSV in MARC-145 cells.

Interestingly, activation of the PPAR-gamma pathway was previously found to downregulate the expression of IFN-gamma activated genes [ 37].

Moreover, apart from its inhibitory action on PTKs, genistein was found to downregulate the expression of VEGF, a major angiogenic factor in periprosthetic microenvironment.

AR signals have also been found to downregulate the expression of P450 CYP4B1 [ 27], UDP-glucuronosyltransferases (UGTs) [ 28], and GATA3 [ 29], all of which are known to prevent urothelial tumorigenesis.

In conclusion, Tyrphostin AG1024 was found to downregulate the expression of Bcr-Abl and P-Akt, and to upregulate the DNA-PKcs protein expression in BCR-ABL expressing cells.

Some cytokines, including IL-6 and interferon-γ, have been found to downregulate the gene expression of sucrase isomaltase.

HACC-loaded PMMA was found to downregulate the virulence-associated gene expression of antibiotic-resistant staphylococci.

In addition, SeSp was found to downregulate the Akt/mTOR pathway by decreasing p-Akt expression and the downstream expression of p-mTOR.

Moreover, artificially designed antisense RNAs have become powerful tools to downregulate the expression of targeted genes.

C/EBP-β expression vectors were also found to downregulate the reporter construct containing the promoter and enhancer of the type II collagen gene.