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Interestingly, Wnt3a treatment alone was actually found to decrease the expression of smooth muscle α-actin in their study.
Cisplatin was found to decrease the expression of the TauT through the activation of p53 in proximal tubular renal cells [ 41].
Some BIMEs, when inserted into operons, have been found to decrease the expression of downstream CDSs through acting as transcriptional attenuators [ 6].
Exercise has been found to decrease the expression of inducible nitric oxide synthase (iNOS), as well as TNF- α, in the colon of azoxymethane- (AOM-) treated mice [ 84].
Combined treatment of drug-naive WM164 cells with both PLX4720 and U0126 was found to decrease the expression of cyclin D1 and enhance the level of PLX4720-induced Pand and caspase-3 cleavage.
Surprisingly, a link between MCs and skin barrier defects was recently uncovered, with histamine – the best known MC mediator - being found to decrease the expression of tight junction proteins, leading to the formation of a defective skin barrier [ 30].
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Accordingly, targeted MO knockdown was found to decrease gene expression levels down to ∼15 30% of normal.
Our results showed that bFGF and serum acted as inhibitors of miR-21 expression, as treatment with these molecules was found to decrease miR-21 expression.
Also, the expression levels of these genes were found to decrease in animal models of Parkinson's disease [ 31].
The expression of vav1 was found to decrease after NICD transfection.
After expression detection of transcriptional suppressors, ZEB1 was found to decrease most significantly.
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